Currently the Executive Director of the Arizona Regional Economic Development Foundation, Mignonne graduated from Tombstone Union High School, attended the University of Arizona, and went on to earn her MBA from the University of Phoenix. In her effort to support economic development in Arizona, Mignonne co-writes a weekly newspaper advice column for business owners, serves on the Chiricahua Community Health Centers, Inc. board, as well as on the Premier Alliances board. She is on the board of the International Economic Development Council and the immediate past President of the Arizona Association for Economic Development. She has served on the Arizona Commerce Authority board and the Greater Arizona Development Board. In 2014, she was named economic developer of the year and her organization was named small organization of the year in 2017. Most recently she was appointed to the State Bar of Arizona Board of Governors, the International Boundary and Water Commission, and serves on the National Small Business Association Advisory Board. Additionally, she serves on the U.S. Global Leadership Coalition, and is a Flinn Brown Fellow. Mignonne is the founder of Aerospace Arizona Association and through this association has formed the UAS Center for Innovation at the Benson Airport. Through her organization, she also created Rural Care which serves as a telehealth office as well as an incubator for mental health providers. Mignonne is dedicated to making an economic impact not only in rural Arizona, but throughout the entire state.